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Awarded Trial: 98-RC-301-5

Grant ID

98-RC-301-5

Illness

Bipolar Disorder and Cocaine/Stimulant Abuse/Dependence

Primary Drug/Intervention

Lamotrigine

Primary Dosage

N/A

Secondary Drug Intervention

N/A

Secondary Dosage

N/A

Other Drug/Intervention

N/A

Other Dosage

N/A

Status

Completed

Investigator

Rush

Sample Size

80

Duration of Study Period for Each Subject

12 weeks

Outcome Measurements

HRSD, YMS, BPRS, Cocaine Craving Questionnaire

Results

Patients with bipolar disorder and comorbid cocaine or stimulant abuse or dependence received adjunctive treatment with lamotrogine. There were significant improvements in all outcome measurements and a reduction in spending for cocaine.

Publication

N/A

Link

N/A

PI Name

John Rush

Degree

MD

Center

UT Southwestern Medical Center

Institution

N/A

Address

N/A

City or Town

Dallas

State or Province

TX

Zip or Postal Code

N/A

Country

USA

Email Address

john.rush@utsouthwestern.edu