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Awarded Trial: 08TGF-1189

Grant ID

08TGF-1189

Illness

Schizophrenia

Primary Drug/Intervention

Pregnenolone

Primary Dosage

50 mg/day

Secondary Drug Intervention

N/A

Secondary Dosage

N/A

Other Drug/Intervention

N/A

Other Dosage

N/A

Status

Completed

Investigator

Ritsner

Sample Size

60

Duration of Study Period for Each Subject

56 days

Outcome Measurements

PANSS, CGI, SANS, The Calgary Depression Scale, Barnes Akathisia Scale, Global Assessment of Functioning, Quality of Life Scale, The CANTAB battery

Results

Gave pregnenolone 50 mg or placebo to 60 recent-onset schiz or schizoaffective patients for 8 wks. Reported significant improvement in negative symptoms (PANSS), quality of life (QLS scale), and global assessment of functioning (GAF).

Publication

N/A

Link

N/A

PI Name

Michael Ritsner

Degree

MD

Center

Sha'ar Menashe Mental Health Center

Institution

The Rappaport Faculty of Medicine, Technion Institute

Address

Sha'ar Menashe MHC, Mobile Post Hefer 38814

City or Town

Hadera

State or Province

N/A

Zip or Postal Code

38814

Country

Israel

Email Address

ritsner@sm.health.gov.il