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Awarded Trial: 06TGF-960
40 IU (delivered doses twice daily)
Secondary Drug Intervention
Duration of Study Period for Each Subject
PANSS, HAM-A, CDSS, GAF, CGI
Twenty (20) patients were included and 15 completed the 7-week trial. Each patient was given oxytocin nasal spray for 3 weeks and a placebo nasal spray for 3 weeks, with a 1-week washout period between treatments. The oxytocin treatment period resulted in a significant improvement in PANSS total, more marked for positive, than for negative, symptoms. The effect was seen only at the end of the 3-week trial, suggesting that a longer treatment period might produce more improvement.
UCSD Medical Center
200 W. Arbor Dr.
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