Back to Awarded Treatment Trials


Awarded Trial: 03T-422

Grant ID

03T-422

Illness

Schizophrenia

Primary Drug/Intervention

Raloxifene

Primary Dosage

60 mg

Secondary Drug Intervention

Hormone Replacement Therapy (HRT)

Secondary Dosage

N/A

Other Drug/Intervention

N/A

Other Dosage

N/A

Status

Completed

Investigator

Kulkarni

Sample Size

60

Duration of Study Period for Each Subject

3 months

Outcome Measurements

PANSS, cognitive battery, hormone assays, MADRS, involuntary movement ratings

Results

Twenty-four post-menopausal women completed the study. Nine women received raloxifene, seven received HRT and eight received placebo. There were no significant differences between groups on psychopathology ratings. Patients treated with raloxifene had a significant improvement on the discrimination index of the Hopkins verbal learning test, but no other cognitive measures.

Publication

N/A

Link

N/A

PI Name

Jayashri Kulkarni

Degree

PhD

Center

Alfred Psychiatry Research Centre

Institution

The Alfred Hospital

Address

Level 1, Old Baker Building, P.O. Box 315

City or Town

Prahran

State or Province

Victoria

Zip or Postal Code

3181

Country

Australia

Email Address

jayashri.kulkarni@med.monash.edu.au