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Awarded Trial: 03T-340

Grant ID

03T-340

Illness

Bipolar Depression

Primary Drug/Intervention

Cytidine

Primary Dosage

1 gm bid

Secondary Drug Intervention

N/A

Secondary Dosage

N/A

Other Drug/Intervention

N/A

Other Dosage

N/A

Status

Completed

Investigator

Lyoo

Sample Size

80

Duration of Study Period for Each Subject

12 weeks

Outcome Measurements

HDRS, YMRS, CGI

Results

Sixty-seven patients with bipolar depression were randomized and 48 patients completed the study. The addition of cytidine produced a significant reduction in depression ratings for weeks 1-4 that did not persist through the remainder of the trial. The addition of cytidine did not result in a greater overall number of patients achieving response or remission.

Publication

N/A

Link

N/A

PI Name

In Kyoon Lyoo

Degree

MD

Center

Seoul National University Hospital

Institution

Seoul National University Hospital, Dept. of Psychiatry

Address

28 Yongon-dong, Chongro-gu

City or Town

Seoul

State or Province

N/A

Zip or Postal Code

110-744

Country

South Korea

Email Address

inkylyoo@yahoo.com