Awarded Trial: 02T-181
Secondary Drug Intervention
Duration of Study Period for Each Subject
HAM-D, YMRS, CGI-BP, UKU side-effects scale
Twenty eight patients completed the trial. Patients receiving celecoxib had a significant improvement on depression ratings at week 1, which did not persist in the subsequent weeks of the trial.
Nery FG, Monkul ES, Hatch JP, Fonseca M, Zunta-Soares GB, Frey BN, Bowden CL, Soares JC. Celecoxib as an adjunct in the treatment of depressive or mixed episodes of bipolar disorder: a double-blind, randomized, placebo-controlled study. Hum Psychopharmacol. 2008 Mar;23(2):87-94.
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