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Awarded Trial: 02-STN-001
up to 200 mg
Secondary Drug Intervention
up to 15mg
Duration of Study Period for Each Subject
PANSS, MADRS, Barnes-akathisia
Ten patients were randomized, all 5 of the patients in the olanzapine group completed the study and they exhibited significant improvements on positive, negative and general symptom ratings. None of the patients receiving amoxapine completed the study, and 4 of 5 withdrew due to lack of efficacy. Because of the high withdrawal rate in the amoxapine group randomization was terminated.
Fitzgerald PB, Filia S, De Castella A, McBain N, Kapur S, Kulkarni J. Amoxapine in schizophrenia: a negative double-blind controlled trial. J Clin Psychopharmacol. 2004 Aug;24(4):448-50.
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