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Awarded Trial: 02-STN-009

Grant ID

02-STN-009

Illness

Schizophrenia

Primary Drug/Intervention

Tamoxifen

Primary Dosage

up to 80 mg per day

Secondary Drug Intervention

N/A

Secondary Dosage

N/A

Other Drug/Intervention

N/A

Other Dosage

N/A

Status

Completed

Investigator

Lieberman

Sample Size

26

Duration of Study Period for Each Subject

4 weeks

Outcome Measurements

PANSS, CGI, CRRS, YMRS

Results

Twenty six subjects with treatment-refractory schizophrenia or schizoaffective disorder were randomized to receive tamoxifen (up to 80 mg per day) or placebo for 4 weeks. Patients continued to take standard antipsychotics. There was no significant difference on PANSS, CGI, CRRS, YMRS or side effect rating scales between placebo or tamoxifen.

Publication

N/A

Link

N/A

PI Name

Jeffrey Lieberman

Degree

MD

Center

N/A

Institution

University of North Carolina

Address

CB # 7160, 7025 Neurosciences Hospital

City or Town

Chapel Hill

State or Province

NC

Zip or Postal Code

27599

Country

USA

Email Address

jlieberman@unc.edu