Back to Awarded Treatment Trials
Awarded Trial: 00-137
Grant ID
00-137
Illness
BP
Primary Drug/Intervention
Vagal Nerve Stimulation (VNS)
Primary Dosage
N/A
Secondary Drug Intervention
N/A
Secondary Dosage
N/A
Other Drug/Intervention
N/A
Other Dosage
N/A
Status
Completed
Investigator
Suppes
Sample Size
9
Duration of Study Period for Each Subject
40 weeks
Outcome Measurements
HRSD, MDRS, CGI, GAF
Results
Nine-patients were treated for 40 weeks with open label VNS. A significant improvement was noted for overall illness and depression symptoms assessed with life-charting methodology, other depression rating scales (HRSD, MDRS).
Publication
Marangell LB, Suppes T, Zboyan HA, et al. A 1-year pilot study of vagus nerve stimulation in treatment resistant rapid-cycling bipolar disorder. J Clin Psychiatry 2008;69:183-189.
Link
http://www.ncbi.nlm.nih.gov/pubmed/18211128
PI Name
Trisha Suppes
Degree
MD
Center
UT Southwestern Medical Center
Institution
University of Texas
Address
5323 Harry Hines Boulevard
City or Town
Dallas
State or Province
TX
Zip or Postal Code
75390
Country
USA
Email Address
Trisha.suppes@UTSouthwestern.edu