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Awarded Trial: 06TGF-911
Secondary Drug Intervention
Duration of Study Period for Each Subject
PANNS, CGI, ANS, CDSS, HAM-A, SUMD, GAF, the Talbieh Brief Distress Inventory, the State/Trait Anxiety Inventory, QLS, Q-LES-Q, ESRS, BARS, CANTAB
Sixty (60) patients with schizophrenia or schizoaffective disorder were randomized to L-theanine 400 mg/day for 8 weeks as an adjunct medication. Those on L-theanine had a significant improvement in anxiety, PANSS-positive, and general psychopathology symptoms.
Ritsner MS, Miodownik C, Ratner Y, Shleifer T, Mar M, Pintov L, Lerner V. L-Theanine relieves positive, activation, and anxiety symptoms in patients with schizophrenia and schizoaffective disorder: an 8-week, randomized, double-blind, placebo-controlled, 2-center study. J Clin Psychiatry. 2011 Jan;72(1):34-42.
Sha'ar Menashe Mental Health Center
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