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Awarded Trial: 01T-437
Secondary Drug Intervention
Duration of Study Period for Each Subject
PANSS, CGI, NOSIE
Fifty eight patients with schizophrenia and residual psychosis despite treatment with 3 neuroleptics were randomized. Thirty three patients completed the study. Clotiapine was superior to chlorpromazine on PANSS ratings (16% vs -1.6% change from baseline), CGI ratings (16.9% vs. 0%) and NOSIE ratings (10% vs. -3%).
Geller V, Gorzaltsan I, Shleifer T, Belmaker RH, Bersudsky Y. Clotiapine compared with clozapine in chronic schizophrenia. Schizophr Res. 2005 Dec 15;80(2-3):343-7.
Beersheva Mental Health Center
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