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Awarded Trial: 98-RC-991
Grant ID
98-RC-991
Illness
Schizophrenia
Primary Drug/Intervention
Trimethoprim
Primary Dosage
200 mg
Secondary Drug Intervention
N/A
Secondary Dosage
N/A
Other Drug/Intervention
N/A
Other Dosage
N/A
Status
Completed
Investigator
Alem
Sample Size
100
Duration of Study Period for Each Subject
6 months
Outcome Measurements
PANSS
Results
Ninety-one patients were randomized and 79 completed the study. There were no significant differences between trimethoprim and placebo.
Publication
Shibre T, Alem A, Abdulahi A, Araya M, Beyero T, Medhin G, Deyassa N, Negash A, Nigatu A, Kebede D, Fekadu A. Trimethoprim as adjuvant treatment in schizophrenia: a double-blind, randomized, placebo-controlled clinical trial. Schizophr Bull. 2010;36:846-851.
Link
http://www.ncbi.nlm.nih.gov/pubmed/19193743
PI Name
Atalay Alem
Degree
MD
Center
Amanuel Psychiatric Hospital
Institution
Addis Ababa University
Address
PO Box 9086
City or Town
Addis Ababa
State or Province
N/A
Zip or Postal Code
N/A
Country
Ethiopia
Email Address
atalayalem@yahoo.com