Awarded Trial: 02T-170
Secondary Drug Intervention
Duration of Study Period for Each Subject
CGI, HAM-D, HAM-A, BPRS, Visual Analogue Scale
One hundred twenty-four patients were randomized to treatment and 77 completed 8 weeks of treatment. Patients receiving T3 were more likely to achieve a response (37%) than those receiving placebo (25%) and were also more likely to achieve remission (34% vs. 21%).
Cooper-Kazaz R, Apter JT, Cohen R, Karagichev L, Muhammed-Moussa S, Grupper D, Drori T, Newman ME, Sackeim HA, Glaser B, Lerer B. Combined treatment with sertraline and liothyronine in major depression: a randomized, double-blind, placebo-controlled trial. Arch Gen Psychiatry. 2007 Jun;64(6):679-88.
Biological Psychiatry Laboratory, Department of Psychiatry
Hadassah-Hebrew University Medical Center
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