Back to Awarded Treatment Trials
Awarded Trial: 01T-069
Grant ID
01T-069
Illness
Bipolar Disorder and Schizophrenia
Primary Drug/Intervention
Mirtazapine
Primary Dosage
<=15mg
Secondary Drug Intervention
Propranolol
Secondary Dosage
<=80mg
Other Drug/Intervention
N/A
Other Dosage
N/A
Status
Completed
Investigator
Poyurovsky
Sample Size
26
Duration of Study Period for Each Subject
2 weeks
Outcome Measurements
BPRS, CGI, HAM-D, BARS, LAS, SAS
Results
Twenty six patients with schizophrenia and neuroleptic induced akathisia received adjunctive mirtazapine (15mg/day) or placebo for 5 days in a double blind design. The mirtazapine treated patients showed significant benefits on the Barnes Akathisia Scale.
Publication
Poyurovsky M, Epshtein S, Fuchs C, Schneidman M, Weizman R, Weizman A. Efficacy of low-dose mirtazapine in neuroleptic-induced akathisia: a double-blind randomized placebo-controlled pilot study. J Clin Psychopharmacology 23:305-308, 2003.
Link
http://www.ncbi.nlm.nih.gov/pubmed/12826992
PI Name
Michael Poyurovsky
Degree
MD
Center
N/A
Institution
Tirat Camel Mental Health Center
Address
9 Eshkol Street
City or Town
Tirat Camel
State or Province
N/A
Zip or Postal Code
30200
Country
Israel
Email Address
tyrmichael@matat.health.gov.il