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Awarded Trial: 01-045
Grant ID
01-045
Illness
Bipolar Disorder
Primary Drug/Intervention
Carnitine
Primary Dosage
15 mg/kg/day
Secondary Drug Intervention
N/A
Secondary Dosage
N/A
Other Drug/Intervention
N/A
Other Dosage
N/A
Status
Completed
Investigator
Elmslie
Sample Size
60
Duration of Study Period for Each Subject
26 weeks
Outcome Measurements
weight change
Results
Forty four patients with bipolar disorder received carnitine supplementation or placebo as an adjunct to sodium valproate to assess the effects weight gain. There was no significant difference between carnitine and placebo on a variety of measures of weight and body composition.
Publication
Elmslie JL, Porter RJ, Joyce PR, Hunt PJ, Mann JI. Carnitine does not improve weight loss outcomes in valproate-treated bipolar patients consuming an energy-restricted, low-fat diet. Bipolar Disord. 2006;8:503-507
Link
http://www.ncbi.nlm.nih.gov/pubmed/17042889
PI Name
Jane Elmslie
Degree
PhD
Center
Department of Psychological Medicine
Institution
University of Otago-Terrace House
Address
4 Oxford Terrace
City or Town
Christchurch
State or Province
N/A
Zip or Postal Code
N/A
Country
New Zealand
Email Address
jane.elmslie@chmeds.ac.nz