Awarded Trial: 00-310
Secondary Drug Intervention
Duration of Study Period for Each Subject
CARS-M, PANSS, MADRS, AIMS
6 women received tamoxifen and 4 women received progesterone. Patients receiving tamoxifen made a better, faster recovery than those receiving progesterone or placebo. Adequate statistical interpretation of the data could not be achieved due to small sample size.
Psychoneuroendocrinology. 2006 May;31(4):543-7. Epub 2005 Dec 13. A pilot study of hormone modulation as a new treatment for mania in women with bipolar affective disorder. Kulkarni J1, Garland KA, Scaffidi A, Headey B, Anderson R, de Castella A, Fitzgerald P, Davis SR.
Alfred Psychiatry Research Center
The Alfred Hospital
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